Natalizumab is a monoclonal antibody that targets α4β1 integrin and prevents immune cells from crossing the blood-brain barrier, reducing inflammation in the central nervous system.

Treatment of relapsing forms of multiple sclerosis (MS): multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system, causing inflammation and damage to the myelin sheath that surrounds nerve fibers.
Maintenance therapy for Crohn's disease

Always take this medicine exactly as your doctor or pharmacist has told you.
Check with your doctor or pharmacist if you are not sure.
Your doctor will tell you how to use this medicine. This will depend on your condition and how old you are.
Intravenous (IV) infusion
The Recommended dose is 300 mg every 4 weeks
Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
If you take more than you should, talk to a doctor or go to the hospital straight away.
If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Like all medicines, this medicine can cause side effects, although not everybody gets them, but you may suffer from:

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Your doctor will discuss the possible risks and benefits of using this medicine during pregnancy and breast-feeding

Regular exercise: improves strength, balance, coordination, and reduces fatigue and depression.
Stress management: techniques like deep breathing, meditation, yoga, and spending time in nature.
Balanced diet: rich in whole grains, fruits, vegetables, lean protein, and healthy fats.
Relaxation techniques: deep breathing, meditation, and visualization.
Social support: join support groups, participate in online forums, and seek counseling.
Cognitive training: exercises like computerized cognitive training or working with a cognitive therapist.
Physical therapy: improves mobility, balance, coordination, and physical function.
Yoga/stretching: improves flexibility, balance, and coordination, and reduces muscle tension and fatigue.
Manage fatigue: pacing activities, taking breaks and developing an energy conservation plan.
Creative activities: art, music, or writing to reduce stress, improve mood, and enhance well-being.

Store in a refrigerator at 2°C to 8°C (36°F to 46°F)
Do not freeze
Keep this medicine out of the sight and reach of children.
Store in the original package to protect it from moisture.
Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

Tysabri, 300 Mg/15 Ml - 1 Vial

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