Ruxolitinib inhibits the Janus kinases (JAKs) signaling pathway. It acts by specifically targeting JAK1 and JAK2, which are involved in the signaling of various proinflammatory and immune regulatory cytokines. By inhibiting this pathway, Ruxolitinib helps to reduce inflammation and regulate immune responses.

Primarily used in the treatment of various inflammatory and autoimmune disorders, including:

Myelofibrosis: A rare bone marrow disorder characterized by the abnormal production of blood cells.
Polycythemia Vera: A chronic blood disorder where the bone marrow makes too many red blood cells.
Graft-Versus-Host Disease: A condition that can occur after a stem cell or bone marrow transplant when the donor's immune cells attack the recipient's tissues.

The typical dosage for Celezon tablets is one tablet taken orally once daily.
It can be taken with or without food.
Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
If you take more than you should, talk to a doctor or go to the hospital straight away.
If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Like all medicines, this medicine can cause side effects, although not everybody gets them, but you may suffer from:

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Your doctor will discuss the possible risks and benefits of using this medicine during pregnancy and breast-feeding

Exercise regularly: Engage in physical activity to improve your overall health and reduce inflammation.
Stress management: Practice mindfulness and relaxation techniques to reduce the impact of stress on your condition.
Dietary choices: Consume an anti-inflammatory diet rich in fruits, vegetables, and whole grains.
Social support: Connect with friends and support groups to share experiences and find emotional support.
Get adequate sleep: Ensure you have enough rest, as sleep is crucial for managing inflammatory and autoimmune disorders.
Avoid smoking: Smoking can worsen inflammation, so quitting is essential for your health.
Limit alcohol consumption: Excessive alcohol can exacerbate symptoms, so moderate your intake.
Manage your weight: Maintain a healthy weight to reduce the strain on your body and joints.
Monitor your condition: Keep regular appointments with your healthcare provider to track your progress.
Stay informed: Educate yourself about your condition and treatment options.

Store below 30°C in a dry place.
Protect from light and moisture.
Keep this medication out of the sight and reach of children.
Store in the original package to protect it from moisture.
Do not use this medication after the expiry date, which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

Celezon, 15 Mg - 56 Tablets

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