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Atacand Plus 16/12.5, For High Blood Pressure - 28 Tablets
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Atacand Plus 16/12.5, Reduce Blood Pressure, Prevent Hypertension Complication - 28 Tablets
Product Name
- Atacand Plus 16/12.5, Reduce Blood Pressure, Prevent Hypertension Complication - 28 Tablets
Scientific Name
- Candesartan 16 Mg + Hydrochlorothiazide 12.5 Mg Tablets
Category Of Atacand Plus 16/12.5 Tablets
- Anti-Hypertensive Drugs
Mechanism Of Action Of Candesartan & Hydrochlorothiazide
- Candesartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to constrict.
- As a result, Candesartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
- Hydrochlorothiazide inhibits sodium chloride transport in the distal convoluted tubule. More sodium is then excreted in the kidney with accompanying fluid.
- Thus it increases urine excretion, which by turn decreases blood volume and finally blood pressure.
- On long-term usage, thiazide diuretic (TZD)-mediated chronic reduction of arterial pressure is thought to occur through decreased total peripheral vascular resistance.
Therapeutic Indications Of Atacand Plus 16/12.5 Tablets
- Treating high blood pressure (hypertension) in adult patients when monotherapy with candesartan cilexetil or hydrochlorothiazide is not sufficient.
- High blood pressure is a common condition in which the long-term force of the blood against your artery walls is high enough that it may eventually cause health problems, such as heart disease.
- Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
Method Of Administration Of Atacand Plus 16/12.5 Tablets
- Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
- The tablets should be swallowed whole with a glass of water.
- You should try to take your daily dose at about the same time each day.
- You must continue to take the drug until your doctor tells you otherwise.
- Do not break the tablet in half
- You can take the tablet with or without food.
- The recommended dose is once daily but your doctor may increase the dose to reaches the targeted blood pressure
- Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
- If you take more than you should, talk to a doctor or go to the hospital straight away.
- If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
- Do not take a double dose (two doses at the same time) to make up for the forgotten dose.
Undesirable Side Effects Of Atacand Plus 16/12.5 Tablets
- In controlled clinical studies with candesartan cilexetil/hydrochlorothiazide, adverse events were mild and transient & include:
- Blood and lymphatic system disorders: Leukopenia, neutropenia, and agranulocytosis.
- Metabolism and nutrition disorders: Hyperkalemia and hyponatremia.
- Nervous system disorders: Dizziness, headache.
- Gastrointestinal disorders: Nausea.
- Hepato-biliary disorders: Increased liver enzymes, abnormal hepatic function, or hepatitis.
- Skin and subcutaneous tissue disorders: Angioedema, rash, urticaria, pruritus.
- Musculoskeletal, connective tissue, and bone disorders: Back pain, arthralgia, myalgia.
- Renal and urinary disorders: Renal impairment, including renal failure in susceptible patients
Pregnancy & Breastfeeding Precautions While Taking Atacand Plus 16/12.5 Tablets
- If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Non-Pharmacological Treatments & Advice To Reduce Blood Pressure
- To measure blood pressure correctly:
- Don’t eat or drink anything 30 minutes before you take your blood pressure.
- Empty your bladder before your reading.
- Sit in a comfortable chair with your back supported for at least 5 minutes before your reading.
- Put both feet flat on the ground and keep your legs uncrossed.
- Rest your arm with the cuff on a table at chest height.
- Make sure the blood pressure cuff is snug but not too tight. The cuff should be against your bare skin, not over clothing.
- Do not talk while your blood pressure is being measured.
- You will also find the following Non-Pharmacological treatments effective in blood pressure reduction:
- Lose extra pounds and watch your waistline
- Exercise regularly
- Eat a healthy diet
- Reduce sodium in your diet
- Quit smoking
- Reduce caffeine
- Reduce your stress
- Monitor your blood pressure at home using for example Beurer, Blood Pressure Monitor or Omron Blood Pressure Measuring Device
- See your doctor regularly
Warnings & Special Precautions while Taking Atacand Plus 16/12.5 Tablets
- Don’t use it if you have: Hypersensitivity to the active substance or any of the excipients or sulfonamide-derived drugs (hydrochlorothiazide is a sulfonamide-derived drug).
- Talk to your doctor about all your medical conditions before taking this medicine including:
- If you have kidney problems.
- If you have liver problems.
- If you have heart problems or heart failure.
- If you have gout.
- If you have diabetes.
- If you are vomiting, have recently had severe vomiting, or have diarrhea.
- If you have low blood pressure.
- If you have had a heart attack or stroke.
- If you are taking any of the following medicines: an ACE inhibitor (like Enalapril, Lisinopril, Ramipril) or Aliskiren
- Please tell your doctor or pharmacist if you are using, or have recently used, any other medicines, including medicines obtained without a prescription.
Storage Conditions Of Atacand Plus 16/12.5 Tablets
- Store below 25°c
- Don’t refrigerate
- Keep this medicine out of the sight and reach of children.
- Store in the original package to protect from moisture.
- Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.
Normal Ranges
- Normal: Blood pressure numbers of less than 120/80 mm Hg
- Elevated: is when readings consistently range from 120-129 systolic and less than 80 mm Hg diastolic.
- Hypertension Stage 1: is when blood pressure consistently ranges from 130-139 systolic or 80-89 mm Hg diastolic.
- Hypertension Stage 2: is when blood pressure consistently ranges at 140/90 mm Hg or higher.
- Hypertensive crisis: This stage of high blood pressure requires medical attention. If your blood pressure readings suddenly exceed 180/120 mm Hg, wait five minutes and then test your blood pressure again. If your readings are still unusually high, contact your doctor immediately. You could be experiencing a hypertensive crisis.
For More Information About Candesartan & Hydrochlorothiazide
- Ask your physician or pharmacist
- Visit SFDA website
- Visit Medscape at Information About Candesartan & Hydrochlorothiazide
- Visit Drugs.com at Information About Candesartan & Hydrochlorothiazide
Size | 28 Pcs |
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Brand | ATACAND |
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