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Atacand Plus 16/12.5, For High Blood Pressure - 28 Tablets

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Atacand Plus 16/12.5, Reduce Blood Pressure, Prevent Hypertension Complication - 28 Tablets

Product Name

  • Atacand Plus 16/12.5, Reduce Blood Pressure, Prevent Hypertension Complication - 28 Tablets

 

Scientific Name

  • Candesartan 16 Mg + Hydrochlorothiazide 12.5 Mg Tablets

 

Category Of Atacand Plus 16/12.5 Tablets

  • Anti-Hypertensive Drugs

 

Mechanism Of Action Of Candesartan & Hydrochlorothiazide

  • Candesartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to constrict.
  • As a result, Candesartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
  • Hydrochlorothiazide inhibits sodium chloride transport in the distal convoluted tubule. More sodium is then excreted in the kidney with accompanying fluid.
  • Thus it increases urine excretion, which by turn decreases blood volume and finally blood pressure.
  • On long-term usage, thiazide diuretic (TZD)-mediated chronic reduction of arterial pressure is thought to occur through decreased total peripheral vascular resistance.

 

Therapeutic Indications Of Atacand Plus 16/12.5 Tablets

  • Treating high blood pressure (hypertension) in adult patients when monotherapy with candesartan cilexetil or hydrochlorothiazide is not sufficient.
  • High blood pressure is a common condition in which the long-term force of the blood against your artery walls is high enough that it may eventually cause health problems, such as heart disease.
  • Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.

 

Method Of Administration Of Atacand Plus 16/12.5 Tablets

  • Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
  • The tablets should be swallowed whole with a glass of water.
  • You should try to take your daily dose at about the same time each day.
  • You must continue to take the drug until your doctor tells you otherwise.
  • Do not break the tablet in half
  • You can take the tablet with or without food.
  • The recommended dose is once daily but your doctor may increase the dose to reaches the targeted blood pressure
  • Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
  • If you take more than you should, talk to a doctor or go to the hospital straight away.
  • If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
  • Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

 

Undesirable Side Effects Of Atacand Plus 16/12.5 Tablets

  • In controlled clinical studies with candesartan cilexetil/hydrochlorothiazide, adverse events were mild and transient & include:
  • Blood and lymphatic system disorders: Leukopenia, neutropenia, and agranulocytosis.
  • Metabolism and nutrition disorders: Hyperkalemia and hyponatremia.
  • Nervous system disorders: Dizziness, headache.
  • Gastrointestinal disorders: Nausea.
  • Hepato-biliary disorders: Increased liver enzymes, abnormal hepatic function, or hepatitis.
  • Skin and subcutaneous tissue disorders: Angioedema, rash, urticaria, pruritus.
  • Musculoskeletal, connective tissue, and bone disorders: Back pain, arthralgia, myalgia.
  • Renal and urinary disorders: Renal impairment, including renal failure in susceptible patients

 

Pregnancy & Breastfeeding Precautions While Taking Atacand Plus 16/12.5 Tablets

  • If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

 

Non-Pharmacological Treatments & Advice To Reduce Blood Pressure

  • To measure blood pressure correctly:
  1. Don’t eat or drink anything 30 minutes before you take your blood pressure.
  2. Empty your bladder before your reading.
  3. Sit in a comfortable chair with your back supported for at least 5 minutes before your reading.
  4. Put both feet flat on the ground and keep your legs uncrossed.
  5. Rest your arm with the cuff on a table at chest height.
  6. Make sure the blood pressure cuff is snug but not too tight. The cuff should be against your bare skin, not over clothing.
  7. Do not talk while your blood pressure is being measured.
  • You will also find the following Non-Pharmacological treatments effective in blood pressure reduction:
  1. Lose extra pounds and watch your waistline
  2. Exercise regularly
  3. Eat a healthy diet
  4. Reduce sodium in your diet
  5. Quit smoking
  6. Reduce caffeine
  7. Reduce your stress
  8. Monitor your blood pressure at home using for example Beurer, Blood Pressure Monitor or Omron Blood Pressure Measuring Device
  9. See your doctor regularly

 

Warnings & Special Precautions while Taking Atacand Plus 16/12.5 Tablets

  • Don’t use it if you have: Hypersensitivity to the active substance or any of the excipients or sulfonamide-derived drugs (hydrochlorothiazide is a sulfonamide-derived drug).
  • Talk to your doctor about all your medical conditions before taking this medicine including:
  1. If you have kidney problems.
  2. If you have liver problems.
  3. If you have heart problems or heart failure.
  4. If you have gout.
  5. If you have diabetes.
  6. If you are vomiting, have recently had severe vomiting, or have diarrhea.
  7. If you have low blood pressure.
  8. If you have had a heart attack or stroke.
  9. If you are taking any of the following medicines: an ACE inhibitor (like Enalapril, Lisinopril, Ramipril) or Aliskiren
  • Please tell your doctor or pharmacist if you are using, or have recently used, any other medicines, including medicines obtained without a prescription.

 

Storage Conditions Of Atacand Plus 16/12.5 Tablets

  • Store below 25°c
  • Don’t refrigerate
  • Keep this medicine out of the sight and reach of children.
  • Store in the original package to protect from moisture.
  • Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

 

Normal Ranges

  • Normal: Blood pressure numbers of less than 120/80 mm Hg
  • Elevated: is when readings consistently range from 120-129 systolic and less than 80 mm Hg diastolic.
  • Hypertension Stage 1: is when blood pressure consistently ranges from 130-139 systolic or 80-89 mm Hg diastolic.
  • Hypertension Stage 2: is when blood pressure consistently ranges at 140/90 mm Hg or higher.
  • Hypertensive crisis: This stage of high blood pressure requires medical attention. If your blood pressure readings suddenly exceed 180/120 mm Hg, wait five minutes and then test your blood pressure again. If your readings are still unusually high, contact your doctor immediately. You could be experiencing a hypertensive crisis.

 

For More Information About Candesartan & Hydrochlorothiazide

More Information
Size 28 Pcs
Brand ATACAND
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